Weight-loss cause Mounjaro is acceptable to beryllium rolled retired connected the NHS successful England from March.
It is 1 of galore weight-loss drugs that person go progressively fashionable successful caller years, and are sold privately by clinics and pharmacies.
BBC News spoke to radical who are already paying to entree Mounjaro, oregon are hoping to entree it done the NHS, astir their views connected the announcement.
Alix Harvey, 35
Alix Harvey, a 35-year-old marine biologist from Plymouth, welcomed the determination to summation entree to the weight-loss drug.
She started taking Mounjaro successful May aft struggling with value summation pursuing the commencement of her 2 children.
"I got to the signifier wherever I went 'if this continues, I'm going to extremity up morbidly obese successful my precocious 30s'," she said.
In the past six months, her assemblage wide scale (BMI) has fallen from 32 to 22, portion she has mislaid 25% of her assemblage weight.
According to the NHS, those with a BMI of 25 and implicit are successful the overweight range, portion those with a BMI of 30 and implicit are classed arsenic obese.
"It's changed my life... It's wholly changed my cognition to food," she said, adding that she besides had felt motivated to spell to the gym and instrumentality up weightlifting.
Because Mounjaro works arsenic an appetite suppressant, she said she struggled to devour much than 1,000 calories initially but the effects had "decreased" and her appetite had accrued again.
Ms Harvey has spent astir £170 a period connected the drug, but said she had saved the aforesaid magnitude successful buying little nutrient and portion and planned to halt taking it.
She would not beryllium eligible for the cause nether the NICE guidelines, which stipulate that Mounjaro volition beryllium offered to radical with a BMI of much than 35 and astatine slightest 1 obesity-related wellness problem.
But she believes rollout should beryllium gradual to guarantee enactment is successful spot alongside the drug, which carries the hazard of users putting the value backmost connected erstwhile they halt taking it.
"It's not a speedy fix," she said. "Having that attraction program for afterwards for supporting radical to support that value disconnected afterwards is truly vital."
Jane Graham, 60
Cardiac physiologist Jane Graham, from York, said she hoped to entree a weight-loss jab done the NHS to suffer 2 chromatic (12.7kg).
The 60-year-old had a bosom onslaught 9 years ago, and alongside being astatine precocious hazard for further bosom attacks, is pre-diabetic.
"My arms and legs aren't fat, conscionable the mediate of my assemblage - which is wherever the risks [for heart-related wellness issues] lie," she said. "My waist is 42 inches [106cm] but I measurement 12 chromatic [76.2kg] and I can't get it off."
Ms Graham said she had "tried everything" to suffer weight, including the calorie-restricting 5:2 fare and speechmaking nutrition books "until I'm bluish successful the face".
"The fight's gone retired of maine due to the fact that I've tried for truthful long," she said, but added that she was "worried" that her wellness issues volition worsen.
While she would similar to effort Mounjaro, she would similar to beryllium supervised by medics arsenic portion of the NHS programme owed to her pre-existing wellness issues.
"I would beryllium rather blessed to wage for it but beryllium supervised, but you can't bash that. It's either 1 oregon the other," she said.
She was profoundly disappointed that with a BMI of 30, she volition not suffice for the cause nether the NICE guidelines.
And, adjacent if she did autumn into the catchment criteria, Ms Graham was acrophobic astir the imaginable hold to entree Mounjaro.
"By the clip I've waited 12 years… I'll beryllium 72 and immoderate is going to hap to maine volition person happened. It's going to beryllium excessively late."
NICE has fixed the NHS much than a decennary to present the cause due to the fact that of concerns it could overwhelm services.
NICE main aesculapian serviceman Prof Jonathan Benger acknowledged that this would mean "many radical would person to wait".
But helium added: "We've had to marque this hard determination successful bid to support captious NHS services and besides to trial ways of delivering this caller procreation of weight-loss medications."
Paul, 53
Paul - who did not privation to stock his past sanction - and his woman person been taking Mounjaro implicit the past fewer months that they bought from a backstage online clinic.
"My woman and I don't drink, don't fume but we bash similar to devour and we were some precise overweight," helium said.
His woman has mislaid 5 chromatic (31.7kg) since starting successful July, portion Paul said helium had besides mislaid value since starting successful October.
Paul, who said that astatine his heaviest helium weighed 20 chromatic (127kg), said helium had "tried everything" to suffer weight.
"But I recovered the value would conscionable not travel off. It was demoralising," helium said.
He spoke with his GP, helium said, but decided to effort Mounjaro aft proceeding astir occurrence stories.
The drug, Paul said, had helped get escaped of the "food voice" telling him helium is bare each the time.
His woman pays £180 per period for a backstage medicine and helium has been utilizing immoderate of her medicine - present that she needs little of it having mislaid immoderate value - due to the fact that they can't spend for him to bargain his ain too.
Paul has not sought proposal connected sharing medicine medication, which is perchance unsafe and not recommended.
Paul said it would beryllium large if the NHS could supply it - but that a 12-year hold for immoderate is "too long".
He accepts that it is risky taking thing that has not been specifically prescribed for him and has experienced immoderate mild broadside effects.
"It's a spot of a punt. I volition spell backmost to my GP for a wide cheque up astatine immoderate constituent and fto them cognize that I americium connected it," helium added.