Colonoscopy, Cologuard, other stool tests: Which detects colon cancer? - USA TODAY

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What if you didn't person to get a colonoscopy each decennary from ages 45 to 75? 

No, this isn't an excuse to skip screening for colon cancer, which has been proven to prevention lives. But there are respective alternatives, which astir radical don't cognize overmuch about.

They are called stool tests and they are conscionable arsenic gross arsenic you mightiness imagine, but they tin beryllium done astatine home, mailed into a lab and don't necessitate immoderate peculiar preparation, dissimilar colonoscopy.

Over time, stool tests — including fecal immunochemical tests, oregon FIT, and the heavy advertised Cologuard — can beryllium conscionable arsenic effectual astatine redeeming lives, and they debar immoderate of the down sides of colonoscopies, experts say. The main contented with stool tests is they person to beryllium done much often: FIT annually and Cologuard each 3 years.

No trial is objectively amended than the others. The United States Preventive Services Task Force recommends colonoscopy and stool tests equally for folks ages 45 to 75 and selectively up until 85 for idiosyncratic who is different healthy.

"The champion colorectal crab screening test is the 1 you really take to take," said Dr. Barnett Kramer, a subordinate of the Lisa Schwartz Foundation for Truth successful Medicine, who retired arsenic manager of the National Cancer Institute's part of crab prevention.

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Here are the advantages and disadvantages of the antithetic approaches.

Pros and cons of colonoscopy   

Colonoscopy is considered the golden standard. If idiosyncratic has symptoms similar bleeding oregon problems harvest up with different tests, radical request to get a colonoscopy to fig retired what's going on.

Routine colonoscopies should beryllium done erstwhile a decade. Today, 60% of Americans are up to day connected colonoscopies with different 11% choosing a antithetic investigating method, according to the CDC. 

Colonoscopies besides person drawbacks.

Although the Affordable Care Act requires colonoscopies, similar different screening tests, to beryllium offered astatine nary outgo to the patient, radical are sometimes amazed with a measure for anesthesia aft a colonoscopy, Kramer said. (In China, they often execute the process without anesthesia but successful the U.S. astir doctors volition garbage to bash 1 unless their diligent is retired and little apt to squirm owed to discomfort, helium said.) 

Colonoscopies are unquestionably the champion trial for uncovering polyps, but it's not wide that should beryllium the extremity of screening, said Dr. Douglas Robertson, a professor astatine the Dartmouth Geisel School of Medicine and main of Gastroenterology astatine the VA Medical Center successful White River Junction, VT. 

"I don't privation to discourage radical who person a past of polyps from getting exams and uncovering polyps," said Robertson, who runs a ample proceedings comparing colonoscopy to FIT for the Veterans Administration.

Polyps are growths that whitethorn oregon whitethorn not yet go cancerous, and much than fractional the colonisation has them. "Common consciousness tells you that the immense bulk of radical adjacent with polyps aren't marching disconnected to cancer," helium said.

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Cologuard stool investigating whitethorn beryllium an option   

Cologuard advertises heavy connected TV and has raised consciousness astir the request for colorectal crab screening. This test, which requires radical to cod a poop illustration and message it in, looks for definite high-risk familial mutations arsenic good as blood successful the stool.

A affirmative Cologuard trial could correspond familial mutations successful the stool and that mightiness punctual immoderate doctors to bash much travel up investigating adjacent aft a cleanable colonoscopy. But the request oregon worth of that follow-up is wholly unclear, Robertson said.

As a one-time test, Cologuard volition observe much cancers than FIT, Robertson said, but implicit time, if done annually successful the lawsuit of FIT and each 3 years for Cologuard, "it's a adjacent call. If thing the models thin to favour FIT," helium said.

Cologuard is casual for patients to usage and casual for doctors to construe the results, said Dr. Casey Allen, a surgical oncologist at Allegheny Health Network successful Pennsylvania.

"There's an inducement to the diligent and to the provider," helium said.

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Why FIT whitethorn beryllium the champion of all   

FIT is simply a batch similar Cologuard successful that radical person to vessel disconnected a stool sample. The main downside to FIT, which looks solely for humor successful the stool, is that radical person to instrumentality them annually and immoderate wellness attraction providers don't spot their patients to enactment up to date.

"When fixed a choice, the penchant successful immoderate countries appears to beryllium for FIT," arsenic opposed to either colonoscopy oregon Cologuard, Kramer said. "I conjecture due to the fact that it is little invasive and due to the fact that you tin bash it astatine home." 

Roughly 5% to 7% of FIT tests volition pb to the request for a colonoscopy, compared to 13% to 15% of Cologuard tests, helium said.

FIT is undeniably the cheapest option.

In a caller study, Allen and his colleagues recovered FIT outgo conscionable implicit $17 a year, portion Cologuard outgo Medicare astir $350. (Private insurers are often charged acold more.) A colonoscopy tin easy tally $10,000. Under the Affordable Care Act, each screening tests indispensable beryllium covered by insurers. 

"There's a important outgo savings without changing diligent outcomes," said Dr. Pavan Rao, a wide surgeon astatine Allegheny General Hospital, who led the research. "The driving unit present is to supply acquisition to some patients and superior attraction providers … and to bash a bully occupation of educating them connected the costs versus the benefits of the 2 tests."

With Cologuard and FIT, the outgo of a follow-up colonoscopy, if needed, mightiness not beryllium covered by insurance, due to the fact that it's nary longer a screening test, but a diagnostic.

In the future, it's imaginable that insurers whitethorn necessitate patients to stock the costs of much costly tests that haven't been proven much effectual than cheaper options, Allen said. 

Major wellness attraction organizations, including the Veterans Administration and Kaiser Permanente, connection FIT tests, Robertson said, with Kaiser efficaciously encouraging radical to travel backmost each year. Kaiser has shown a 50% simplification successful colorectal crab mortality among its patients since they started utilizing FIT backmost successful 2008.

Both Robertson and Kramer get yearly FIT tests themselves.

"I'm a FIT enthusiast," Robertson said.

Contact Karen Weintraub astatine kweintraub@usatoday.com.

Health and diligent information sum astatine USA TODAY is made imaginable successful portion by a assistance from the Masimo Foundation for Ethics, Innovation and Competition successful Healthcare. The Masimo Foundation does not supply editorial input.

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