medwireNews: COVID-19 vaccination should beryllium actively promoted for women with rheumatic and musculoskeletal diseases (RMDs) who are large oregon readying a pregnancy, accidental researchers.
Their findings, presented successful a poster astatine ACR Convergence 2022 successful Philadelphia, Pennsylvania, USA, showed a higher complaint of preterm commencement among 47 unvaccinated oregon partially vaccinated (one dose) women with RMD who developed COVID-19 during their gestation than 26 akin women who were afloat vaccinated (two oregon much doses), astatine 29.5% versus 18.2%. The between-group quality did not scope statistical significance, however.
The astir communal RMDs were systemic lupus erythematosus (23%) and rheumatoid arthritis (21.9%), and the bulk (70%) of patients were successful remission erstwhile diagnosed with COVID-19.
At the clip of information extraction, determination were 55 completed pregnancies, 50 of which were unrecorded births. The astir predominant neonatal complication was debased birthweight (<2500 g), occurring successful 24% of unrecorded births, and tiny for gestational property (below the 10th percentile), occurring successful 14%.
Most of the women were unvaccinated erstwhile diagnosed with COVID-19, portion 4% were partially vaccinated and 36% afloat vaccinated.
Hospital admittance was indispensable for 21% of women, careless of vaccination status, but lone 16% needed COVID-19 circumstantial medication.
“This would connote COVID-19 severity was akin betwixt vaccinated and partially vaccinated oregon unvaccinated women,” said Sinead Maguire (St James’ Hospital, Dublin, Ireland) successful a property release. “This was an unexpected result, fixed the differences successful obstetric and neonatal outcomes.”
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