The study, published successful prestigious peer-reviewed diary Biomolecules by MDPI, was conducted done a collaboration betwixt Hofseth BioCare (HBC) and Stanford University School of Medicine. It aimed to further analyse the gastro-intestinal (GI)-protective properties of the bioactive peptides contained successful salmon-derived ProGo®. The preclinical survey recovered that the soluble macromolecule hydrolysate (SPH) powder, produced by HBC’s unsocial enzymatic macromolecule hydrolysis process, helps reconstruct a steadfast equilibrium wrong the gut immune strategy and markedly amended gut wellness successful inflammatory bowel illness (IBD).
The bioactive peptides successful SPH importantly reduced colon insubstantial wounded successful the acute colitis carnal exemplary by alleviating inflammatory compartment infiltrates and oxidative stress, an underlying operator of galore digestive diseases. This points to ProGo® arsenic having a imaginable immunomodulatory enactment done the upregulation of protective, antioxidant cistron pathways including HMOX1.
Prior probe undertaken by HBC and Stanford besides demonstrated that cistron systems which support the GI tract against oxidative accent and inflammation are upregulated successful quality GI cells exposed to SPH. This latest find bolsters ProGo®’s presumption arsenic a fresh, effectual innovation and presents a premier accidental for nutraceutical manufacturers looking to disrupt the gut wellness and immunity markets.
“The peptides that represent ProGo® are proven to not lone present nutritional benefits, specified arsenic collagen for tegument health, but besides a myriad of important wellness benefits, including antioxidant effects to enactment gut wellness and immunity and to prolong wide health,” said Dr Crawford Currie, Head of Medical R&D astatine Hofseth BioCare. “This latest Stanford University survey underpins ProGo®’s estimation arsenic a patented merchandise possessing properties, claims and wellness benefits unsocial to the market. Further objective studies are successful the pipeline to research the efficacy of ProGo® arsenic a functional and targeted instrumentality successful IBD absorption and we look guardant to discovering the afloat imaginable of this genuinely transformative innovation.”
The survey adds to the increasing slope of grounds demonstrating ProGo® is simply a axenic and proven product. The constituent was precocious acknowledged arsenic a ‘New Dietary Ingredient’ (NDI) and secured 7 caller operation relation claims from the US Food and Drug Administration (FDA). These earthy collagen peptides tin present besides assertion to assistance “reduce wrinkles and beforehand tegument smoothness”, “help with adust skin” and “support tegument wellness and appearance”. Furthermore, the grounds of the peptides’ bioactivity tin besides present assertion to “act and an antioxidant”, “reduce oxidative accent caused by escaped radicals” and arsenic good arsenic promoting vigor and sustaining wide wellness and wellbeing.
To work the afloat technological study, click here, oregon interaction the Hofseth BioCare team: Hofseth BioCare | Research and development
About Hofseth BioCare:
HBC is simply a Norwegian user and favored wellness constituent supplier and an incubator for caller cause leads. Research is ongoing to place the idiosyncratic elements wrong its ingredients that modulate inflammation and the immune effect with pre-clinical studies successful aggregate clinics and assemblage probe labs successful respective countries. Lead objective and pre-clinical candidates are focused connected processing an oral pharmaceutical pb programme to dainty inflammatory illness driven by eosinophils. Clinical proceedings enactment to ameliorate lung inflammation successful eosinophilic asthma and COPD ("smokers lung") is planned and proceedings enactment assessing immune wellness enactment is completing successful COVID. Other leads are focused connected the extortion of the Gastro-Intestinal (GI) strategy against inflammation (including ulcerative colitis and the orphan information necrotising enterocolitis) and utilizing peptide fractions of salmon macromolecule hydrolysate (SPH besides known arsenic 'ProGo') arsenic a Medical Food to assistance dainty age- related Sarcopenia, and arsenic a attraction for Iron Deficiency Anemia.
The institution is founded connected the halfway values of sustainability, optimal utilization of earthy resources and afloat traceability. Through an innovative hydrolysis technology, HBC tin sphere the prime of lipids, proteins and calcium from caller salmon off-cuts. Hofseth BioCare's office are successful Ålesund, Norway with branches successful Oslo, London, Zürich, Chicago, Palo Alto and Tokyo.
For further accusation connected HBC, delight contact:
Dr. Crawford Currie, Head of Medical R&D
cc@hofsethbiocare.com
This accusation is considered to beryllium wrong accusation pursuant to the EU Market Abuse Regulation and is taxable to the disclosure requirements pursuant to conception 5-12 of the Norwegian Securities Trading Act. The banal speech announcement was published by Jon Olav Ødegård, CEO of Hofseth BioCare ASA, astatine the day and clip arsenic acceptable retired above.
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