Paxlovid - an antiviral made by Pfizer - is present being looked astatine arsenic a imaginable agelong Covid treatment.
The pharma giant's flagship Covid drug gained exigency support successful the US past December to dainty high-risk patients - slashing their hazard of decease by 90 per cent.
It is presently the lone medicine you tin instrumentality astatine location to dainty Covid and has been fixed to millions of susceptible Americans with underlying wellness conditions.
Now, researchers astatine Stanford are astir to motorboat the archetypal objective proceedings of the cause to spot it whitethorn besides supply alleviation to people who are inactive sick months and years aft clearing the virus.
Prior probe has indicated that radical fixed the cause are a 4th little apt to endure agelong Covid - which astir commonly causes aggravated tiredness, encephalon fog and musculus weakness.
As of yet, determination are nary proven treatments for agelong Covid, and nary 1 knows what causes the ongoing symptoms.
A fashionable mentation is that determination whitethorn beryllium bits of leftover microorganism wreaking havoc successful the body. A caller survey suggested radical with agelong Covid endure physical alterations to their brain months aft clearing the archetypal infection.
More than 15million Americans are officially estimated to person agelong Covid to varying degrees.
Trial participants volition instrumentality the antiviral cause for 10 days longer than radical usually instrumentality it for, to spot if it needs longer to work
What is agelong Covid?
Long Covid is an informal term, utilized to picture ongoing symptoms pursuing a Covid corruption that spell connected longer than 4 weeks, according to the ONS.
A dizzying array of symptoms person been attributed to agelong Covid, including:
- extreme tiredness (fatigue)
- shortness of breath
- chest symptom oregon tightness
- problems with representation and attraction ('brain fog')
- difficulty sleeping (insomnia)
- heart palpitations
- dizziness
- pins and needles
- joint pain
- depression and anxiety
- tinnitus, earaches
- feeling sick, diarrhoea, tummy aches, nonaccomplishment of appetite
- a precocious temperature, cough, headaches, sore throat, changes to consciousness of odor oregon taste
- rashes
There is nary cure for the information though the NHS does urge a fig of treatments designed to assistance alleviate the symptoms.
The caller survey hopes to motion up 200 adults who person been antagonistic for Covid for 3 months yet inactive endure symptoms.
Half the participants volition person Paxlovid and fractional volition instrumentality a placebo.
To dainty an infection, Paxlovid is fixed as six pills a time for 5 days, but participants successful the caller survey volition instrumentality the cause for 15 days to trial the mentation that the cause needs much clip to person its afloat effect.
Results of the proceedings are expected adjacent year.
The archetypal subordinate successful the proceedings was 67-year-old Bill Fimbres from California, who has been suffering with agelong Covid symptoms for a year-and-a-half, including a nonaccomplishment of smell and taste, debilitating fatigue and encephalon fog.
He said: 'It's similar you person idiosyncratic else's brain.'
Mr Fimbres volition instrumentality his archetypal dose of either the cause oregon placebo connected Monday.
He told NBC News: 'If I could get escaped of conscionable 1 of my symptoms, that would beryllium great. I'm conscionable going connected hope.'
Evidence indicating Paxlovid mightiness stunt semipermanent symptoms already exists.
A study by the Department of Veterans Affairs this period suggested those who received the cause instantly aft their Covid diagnosis were 26 per cent little apt than those who did not instrumentality the antiviral to person lasting symptoms 3 months on.
However, the participants were each aged 60 oregon supra with further wellness issues, meaning the findings whitethorn not beryllium applicable to everyone.
Long Covid has puzzled scientists and physicians since it archetypal popped connected their radar successful 2020.
Its causes person not been figured out, but experts judge it could beryllium tied to the body's immune effect to the virus.
There person besides been antecedently known cases of radical suffering semipermanent symptoms aft suffering much communal viruses similar the flu.
The CDC estimates that astir 7.5 per cent of American adults are suffering from agelong Covid symptoms.
Sufferers are mostly nether the property of 50, and are much apt to beryllium women. Reports of agelong Covid are astir communal successful confederate states similar Kentucky and Alabama.