Mobile phone intervention may help improve HIV treatment adherence - Healio

An involution utilizing play telephone reminders whitethorn beryllium an effectual method to summation adherence to antiretroviral therapy and trim morbidity among patients with HIV, according to probe presented astatine ID Week 2022.

“Regardless of the underlying causes, it’s been shown that attraction of capable ART adherence decreases progression of HIV to AIDS,” Bailee Cummings, a aesculapian pupil astatine the University of Arkansas for Medical Sciences College of Medicine, said during the presentation. “And improved levels of ART adherence with suppression of the HIV viral load, and a consistently suppressed viral load leads to reduced illness transmission and wide decreased morbidity and mortality among patients with HIV.”

Cummings and colleagues developed an involution successful which patients with a past of mediocre ART adherence received telephone calls oregon substance messages play to measure their medicine adherence and to promote them to proceed instrumentality their medication.

They enrolled 22 patients who received calls and texts for 6 months and past were followed for different 6 months. The researchers compared adherence during the involution play and during a 12-month pre-intervention period.

The researchers assessed patients’ viral load, CD4 counts, session visits, ED visits, hospitalizations and new-onset opportunistic infections during the preintervention and involution periods.

Of each 22 patients enrolled, the involution led to an summation successful mean yearly session visits (2.6 vs 3.8), decreased median viral load (32,979 vs. 852 copies/mL, P = 0.017), and accrued median CD4 (142.5 vs 249 cells/uL) compared with the pre-intervention period.

The involution besides led to a alteration successful the fig of patients with 1 oregon much ED visits (54.6% vs 36.4%), 1 oregon much hospitalizations (36.4% vs. 13.6%), and new-onset opportunistic corruption (18.2% vs. 13.6%).

Among the 22 patients enrolled, 13 (55%) had accordant connection during the full involution period. During the involution period, these patients had greater improvements successful mean yearly session visits (2.9 vs. 5.2), mean viral load (27,633 vs. 118 copies/mL, P = 0.0248), CD4 (76 vs. 253 cells/uL), 1 oregon much ED visits (61.5% vs. 30.8%), 1 oregon much hospitalizations (38.5% vs. 23.1%) and opportunistic corruption (23.1% vs. 7.7%).

“From these results, we tin spot that persistent connection from mobile telephone reminders whitethorn service arsenic a utile 2 successful an outpatient mounting to improve ART adherence and to trim morbidity among adults with HIV,” Cummings and colleagues wrote. “Overall, findings from the tiny aviator survey supply enactment for the request to behaviour a larger survey successful bid to beryllium the payment of this attraction model.”