New EndoGlide technique in treatment for Fuchs' dystrophy shows promise - Ophthalmology Times

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After comparing 2 techniques of corneal transplant insubstantial preparation, probe shows a newer, faster method is harmless and effective.

Descemet’s membrane endothelial keratoplasty (DMEK), has emerged arsenic an effectual attraction for patients with Fuchs’ dystrophy.

According to researchers in the Department of Ophthalmology at University of Colorado School of Medicine, a newer, faster method for preparing corneal insubstantial for transplantation has been shown to beryllium harmless and effective.

Recently, partial-thickness corneal transplantation, oregon Descemet’s membrane endothelial keratoplasty (DMEK), has emerged arsenic an effectual attraction for patients with Fuchs’ dystrophy, a information successful which endothelial cells dice off. During DMEK surgery, the surgeon lone removes and replaces the damaged interior furniture of the cornea, decreasing risks of transplant rejection with imaginable for fantabulous vision.

“It’s a large process due to the fact that it has fantastic ocular outcomes and a overmuch little hazard of transplant problems down the roadworthy compared with older transplant techniques,” says Karen Christopher, MD, adjunct prof of ophthalmology successful the CU School of Medicine and pb author for the study1 recently published successful the journal Cornea. “It tin truly reconstruct vision-related prime of beingness for patients who endure from symptoms of Fuchs' dystrophy, and our probe shows we tin bash this much successfully present than ever before.”

Christopher led the CU probe squad which compared antithetic ways of preparing cornea insubstantial for DMEK transplantation. One method utilized a comparatively caller instrumentality called the DMEK EndoGlide, and 1 with a instrumentality called a Jones tube, modified from a solid conduit that had been utilized successful teardrop drainage surgery. The probe was conducted astatine the Rocky Mountain Lions Eye Bank, which prepared and past gathered information for 30 DMEK grafts utilized successful the study.

The EndoGlide method preserves the insubstantial successful a tiny capsule and forceps are aboriginal utilized to propulsion the insubstantial into the oculus during surgery. According to the study, this method performed comparably to the modified Jones conduit technique, which has been utilized for DMEK country for galore years.

According to Christopher, this is the archetypal nonstop examination betwixt the Jones conduit and the EndoGlide technique, the second of which she says provides much power for the surgeon during the transplantation. This leads to faster and much regulated insubstantial implantation.

References:
1. Christopher, Karen L. MD*; Terrin, Staci CEBT†; Lohmeier, John BA, CEBT†; Hartman, Matthew MD*; Davidson, Richard S. MD*; Taravella, Michael J. MD. Comparison of the Modified Jones Tube Technique and the DMEK EndoGlide Technique With and Without Viscoelastic Material for DMEK Tissue Preparation. Cornea; 42(2): p 247-251, Published February 2023. DOI: 10.1097/ICO.0000000000003178
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