The COVID-19 pandemic stimulated an unprecedented propulsion for integer transformation, accelerating the adoption of integer exertion successful wellness care1. There was a surge successful telemedicine services, successful artificial quality (AI) for SARS-CoV-2 detection2, and successful the usage of AI to foretell blueprints for vaccine development3. With the accrued integer travel of data, determination is simply a request for privacy-preserving technologies to amended probe and objective applications wrong the healthcare system4,5. Data tokenization connected the blockchain provides precocious levels of privateness and confers the imaginable for idiosyncratic ownership of wellness data, which different privacy-preserving technologies specified arsenic federated learning and generative adversarial networks bash not offer6,7,8 (see Table 1 for a glossary of terms). The usage of non-fungible tokens (NFTs) is simply a imaginable data-management solution for the governance of information astatine some idiosyncratic and organization levels.
Tokenization is simply a data-security method and token types see level tokens, inferior tokens, governance tokens, information tokens, and NFTs. NFTs are supported connected blockchain platforms specified arsenic Ethereum and Hyperledger Fabric, wherever each NFT is digitally unique. NFTs tin beryllium created via the minting of existing integer data, oregon they tin usage generative data, wherever the integer merchandise is produced successful full oregon successful portion by an autonomous system. Once encoded with blockchain technology, a NFT cannot beryllium modified, and its authenticity is validated done the blockchain successful which it is stored. Hence, anterior to minting, information indispensable beryllium cleaned, verified by verifiable credentials, and converted into an actionable form. This allows individuals to ain and commercialized integer assets betwixt parties specified arsenic multinational aesculapian networks, pharmaceutical companies oregon security companies (Fig. 1).
We envisage respective imaginable benefits of healthcare information tokenization successful the signifier of NFTs. Ownership of information by patients whitethorn effect successful safer attraction by improving the fluidity of wellness accusation amongst antithetic attraction providers. At present, rules astir the extortion of information privateness restrict the sharing of diligent information crossed institutions, and inaccurate oregon incomplete accusation tin effect successful misdiagnosis and suboptimal care. Patient entree and ownership of information mightiness flooded this situation. This accrued fluidity of wellness accusation whitethorn render wellness economical benefits by reducing duplicate investigations oregon treatment.
Giving patients ownership and entree to their wellness information mightiness besides promote diligent engagement successful their care9, which tin positively impact attraction compliance. Similarly, tokenization of wellness information allows patients to workout autonomy implicit their ain data, which could forestall companies from profiting from information aggregated via idiosyncratic wellness applications, oregon unauthorized entree to organization databases by 3rd parties who past merchantability delicate wellness information. Instead, patients tin actively take to stock idiosyncratic information for research. This could code ongoing ethical concerns surrounding situations successful which AI developers usage publically disposable diligent information to make AI algorithms that tin beryllium monetized, without the patients being financially rewarded.
Storing wellness information arsenic NFTs tin besides guarantee information authenticity by preventing modifications erstwhile information person undergone minting. Data integrity contributes to prime wellness attraction during objective decision-making processes and volition besides lend to more-accurate findings successful research. The usage of blockchain exertion could besides beryllium utilized for cause verification to forestall counterfeit drugs. The usage of astute contracts wrong NFTs further allows for reliable automation of information exchange. Smart declaration is simply a rule-based algorithm that allows automated self-execution of the support process erstwhile predetermined conditions oregon rules are met, which removes the request for quality input successful the execution process.
To tokenize wellness data, modifications indispensable beryllium made from existing NFT systems. We absorption present connected the minting process and little connected the transactional quality of existing commercialized NFTs. We suggest that a blockchain ledger dedicated to healthcare information is identified oregon created, with tokenized information stored and verified, and wherever the information cannot beryllium publically viewed. This contrasts with existing commercialized NFT marketplaces wherever the integer plus — specified arsenic an creation oregon euphony record — tin beryllium publically viewed, though owned lone by the idiosyncratic who generated oregon bought it.
A web-based oregon smartphone exertion could beryllium created, successful which each diligent has a wellness wallet, akin to a cryptocurrency wallet, wherever tokenized integer wellness information tin beryllium accessed arsenic NFTs via verifiable credentials. The wellness information to beryllium tokenized indispensable beryllium characterized, which volition impact determining whether the information are structured (such arsenic laboratory values) oregon unstructured (such arsenic radiology images and doc notes) and whether preprocessing of the information is required.
Once the infrastructure is ready, wellness information tin beryllium minted arsenic NFTs. Acquired wellness information volition acquisition minting into a wellness NFT and made disposable successful a patient’s wellness wallet. Patients volition past person ownership and entree to their ain information and whitethorn subsequently determine whether to stock oregon transportation ownership of these information to different parties successful the web (Fig. 1).
Despite the imaginable benefits, however, determination are barriers to the adoption of NFTs successful wellness care. NFTs are susceptible to information information compromises owing to vulnerabilities with astute contracts. Stolen NFTs are not uncommon, arsenic seen successful the theft of Bored Ape Yacht Club NFTs, wherever hackers utilized phishing techniques to modify astute contracts. Moreover, tokenization of wellness information could pb to unethical exploitation, with patients being driven to enactment successful tests for monetary gains. In addition, the complexities of NFTs whitethorn airs a situation for immoderate radical successful presumption of managing their ain data.
Destruction of NFTs is imaginable and is done by ‘burning’ astatine present, with NFTs being sent to inaccessible addresses. However, NFTs are mostly regarded arsenic immutable and whitethorn beryllium connected the blockchain forever, posing a situation for the demolition oregon modification of immoderate inaccuracies successful wellness information that mightiness compromise diligent attraction and probe integrity. The minting, transportation and retention of ample amounts of healthcare information tin besides pb to precocious attraction costs and powerfulness consumption, resulting successful an tremendous c footprint10. Minting of NFTs tin alteration successful outgo depending connected the information size, transaction speed, blockchain inferior fees, and information quality. The colossal magnitude of wellness information from the planetary colonisation whitethorn beryllium excessively overmuch for existing infrastructure to support. The nascent exertion of quantum computing whitethorn supply solutions for information storage, retrieval and investigation done quantum speedup and quantum supremacy. Future probe to code these limitations and applicable considerations volition assistance successful the tokenization of wellness data.
NFTs successful wellness attraction could revolutionize however delicate wellness information are handled. At the bosom of NFTs are transparency, accountability, privateness and diligent autonomy — each of which are important values successful wellness care. Further enhancements to safeguard information information and to simplify processes, arsenic good arsenic to summation accessibility to all, volition beryllium indispensable if NFTs are to commencement a gyration successful integer health.
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Competing interests
D.S.W.T. holds a patent connected a deep-learning strategy for the detection of retinal diseases. D.S.W.T. is besides a co-founder of, and holds equity in, EyRIS Singapore. Z.L.T. declares nary struggle of interest.
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Teo, Z.L., Ting, D.S.W. Non-fungible tokens for the absorption of wellness data. Nat Med (2023). https://doi.org/10.1038/s41591-022-02125-2
Published: 23 January 2023
DOI: https://doi.org/10.1038/s41591-022-02125-2