Replay establishes distinguished Scientific Advisory Board of genomic medicine and compartment therapy experts
San Diego, California and London, UK, October 17, 2022 – Replay, a genome penning institution reprogramming biology by penning and delivering large DNA, contiguous announced that it has established a technological advisory committee (SAB) comprising 10 experts crossed a wide scope of areas of technological value successful genomic medicine and compartment therapy.
The recently formed SAB volition supply input into Replay’s strategy, portfolio of next-generation genomic and compartment therapy medicines, and associated exertion platforms. The SAB complements Replay’s manufacture seasoned absorption squad and board.
Adrian Woolfson, Executive Chairman, President and Co-founder of Replay, commented: “The multi-disciplinary quality of our technological advisory committee reflects Replay’s committedness to invoking innovation from a wide scope of technological specialties and leveraging this crossed our probe and improvement programs. Our caller advisors correspond immoderate of the champion technological minds of their procreation and bring a unsocial and differentiated portfolio of expertise into the Company. Their publication to Replay volition beryllium invaluable arsenic we proceed to code immoderate of the astir important challenges successful genomic medicine and compartment therapy.”
Lachlan MacKinnon, Chief Executive Officer and Co-founder of Replay, added: “Following connected from our caller launch, the enactment of our uniquely distinguished technological advisory committee further demonstrates Replay’s committedness to processing a cutting-edge portfolio of medicines guided by world-class science. The combined inter-disciplinary expertise of our technological advisory committee brings tremendous cognition and acquisition into the Company arsenic we proceed to grow our operations, with a presumption to processing transformative genomic medicines.”
Replay’s SAB volition beryllium chaired by Professor Roger Kornberg, PhD, a biochemist whose laboratory enactment has focused connected the molecular ground of eukaryotic transcription and successful peculiar the operation of RNA polymerase and the nucleosome.
Professor Roger Kornberg, PhD, Chairman of Replay’s Scientific Advisory Board, said: “Replay’s technological advisory committee incorporates expertise crossed respective areas applicable to Replay’s genomic medicine and compartment therapy exertion platforms. I americium excited to beryllium moving with this exceptional radical of scientists and judge we tin marque a compelling publication and assistance Replay recognize its imaginativeness for genomic medicine.”
Replay’s SAB members are arsenic follows:
Professor Roger D. Kornberg PhD (Chairman), is the Winzer Professor of Medicine successful the Department of Structural Biology astatine Stanford University School of Medicine. He was awarded the Nobel Prize successful Chemistry (2006).
Professor Carl H. June, MD, is the Richard W. Vague Professor successful Immunotherapy successful the Department of Pathology and Laboratory Medicine astatine the Perelman School of Medicine astatine the University of Pennsylvania. He is Director of the Parker Institute for Cancer Immunotherapy astatine the University of Pennsylvania, Director of the Center for Cellular Immunotherapies astatine the Perelman School of Medicine, and Director of Translational Research astatine the Abramson Cancer Center. He was the co-founder of TMunity.
Professor Robert S. Langer, ScD, FREng, is 1 of 12 Institute Professors astatine the Massachusetts Institute of Technology (MIT), co-founder of Moderna, and was formerly Chair of the FDA’s Science Board. He has been awarded 40 honorary doctorates, written implicit 1,500 articles, and received implicit 220 awards.
Professor Lynne E. Maquat, PhD, is the J. Lowell Orbinson Endowed Chair and Professor of Biochemistry and Biophysics, University of Rochester Medical Center, and founding Director of the Center for RNA Biology, University of Rochester, Rochester NY. She was awarded the Wolf Prize successful Medicine from Israel (2021) and the Warren Alpert Foundation Prize from Harvard Medical School (2021).
Professor Dame Carol Robinson, DBE FRS FMedSci FRSC, is the Dr Lee’s Professor of Physical and Theoretical Chemistry, the Founding Director of the Kavli Institute for Nanoscience Discovery astatine Oxford, and a Founder of OMass Therapeutics. She is simply a Professorial Fellow astatine Exeter College, Oxford, and was formerly President of the Royal Society of Chemistry.
Professor David V. Schaffer, PhD, is the Hubbard Howe Professor of Chemical and Biomolecular Engineering, Bioengineering, and Neuroscience astatine the University of California, Berkeley, wherever helium is Director of the Bakar BioEnginuity Hub and Director of the California Institute for Quantitative Biosciences (QB3). He was the co-founder of 4D Molecular Therapeutics, Ignite Immunotherapies, Rewrite, and 5 further companies.
Professor Stuart L. Schreiber, PhD, is the Morris Loeb Professor of Chemistry and Chemical Biology astatine Harvard University. He is simply a co-founder of the Broad Institute astatine Harvard University and MIT and co-founder of Harvard’s Institute of Chemistry and Cell Biology. He was awarded the Wolf Prize successful Chemistry (2016).
Professor Pamela Silver, PhD, is the Elliot T. and Onie H. Adams Professor of Biochemistry and Systems Biology successful the Department of Systems Biology astatine Harvard Medical School, and a founding subordinate of the Wyss Institute for Biologically Inspired Engineering astatine Harvard Medical School.
Professor Sir John E. Walker, FRS FMedSci, is Emeritus Director and Professor astatine the MRC Mitochondrial Biology Unit astatine the University of Cambridge, England, and a chap of Sidney Sussex College, Cambridge. He was awarded the Nobel Prize successful Chemistry (1997).
Professor John Fraser Wright, PhD, is Professor of Pediatrics, Division of Hematology, Oncology, Stem Cell Transplantation and Regenerative Medicine, and Director of Technology Innovation astatine the Center for Definitive and Curative Medicine astatine Stanford University. He is co-founder and was Chief Technology Officer astatine Spark Therapeutics and is co-founder and Chief Scientific Advisor astatine Kriya Therapeutics.
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About Replay
Replay is simply a genome penning company, which aims to specify the aboriginal of genomic medicine done reprogramming biology by penning and delivering large DNA. The Company has assembled a toolkit of disruptive level technologies – including a precocious payload capableness HSV platform, a hypoimmunogenic compartment therapy platform, and a genome penning level – to code the technological challenges presently limiting objective advancement and preventing genomic medicine from realizing its afloat potential. The Company’s hub-and-spoke concern exemplary separates exertion improvement wrong Replay from therapeutic improvement successful merchandise companies that leverage its exertion platforms. For example, Replay’s synHSV™ technology, a precocious payload capableness HSV vector susceptible of delivering up to 30 times the payload of AAV, is utilized by Replay’s 4 cistron therapy merchandise companies, bringing large DNA treatments to diseases affecting the skin, eye, brain, and muscle. The Company has, additionally, established an enzyme penning merchandise institution that leverages its evolutionary inference instrumentality learning and genome penning exertion to optimize enzyme functionality. Replay is led by a world-class squad of academics, entrepreneurs, and manufacture experts.
The Company raised $55 cardinal successful effect financing successful July 2022 and is supported by an planetary syndicate of investors including: KKR, OMX Ventures, ARTIS Ventures, and Lansdowne Partners.
Replay is headquartered successful San Diego, California, and London, UK. For further accusation delight sojourn www.replay.bio and travel america connected LinkedIn and Twitter.
Contacts:
Replay
Dr Adrian Woolfson/Lachlan MacKinnon
Consilium Strategic Communications – Media relations
Amber Fennell/Tracy Cheung/Andrew Stern
English (US)