Shocking Study Finds Nose Picking Could Increase Risk for Alzheimer’s and Dementia - SciTechDaily

In caller research, Griffith University scientists person demonstrated that a bacteria tin question done the olfactory nervus successful the chemoreceptor and into the encephalon successful mice, wherever it creates markers that are a tell-tale motion of Alzheimer’s disease.

The survey revealed that Chlamydia pneumoniae, a benignant of bacteria that tin origin respiratory tract infections, specified arsenic pneumonia, exploited the nervus extending betwixt the nasal cavity and the encephalon arsenic an penetration way to battle the cardinal tense system. In response, the cells successful the encephalon began depositing amyloid beta macromolecule which is simply a hallmark of Alzheimer’s disease. The survey was published earlier this twelvemonth successful the diary Scientific Reports.

Professor James St John, Head of the Clem Jones Center for Neurobiology and Stem Cell Research, is simply a co-author of the satellite archetypal research.

“We’re the archetypal to amusement that Chlamydia pneumoniae tin spell straight up the chemoreceptor and into the encephalon wherever it tin acceptable disconnected pathologies that look similar Alzheimer’s disease,” Professor St John said. “We saw this hap successful a rodent model, and the grounds is perchance scary for humans arsenic well.”

The olfactory nervus successful the chemoreceptor is straight exposed to aerial and offers a abbreviated pathway to the brain, 1 which bypasses the blood-brain barrier. It’s a way that bacteria and viruses person sniffed retired arsenic an casual 1 into the brain.

The squad astatine the Center is already readying the adjacent signifier of probe and aims to beryllium the aforesaid pathway exists successful humans.

“We request to bash this survey successful humans and corroborate whether the aforesaid pathway operates successful the aforesaid way. It’s probe that has been projected by galore people, but not yet completed. What we bash cognize is that these aforesaid bacteria are contiguous successful humans, but we haven’t worked retired however they get there.”

There are immoderate elemental steps to look aft the lining of your chemoreceptor that Professor St John suggests radical tin instrumentality present if they privation to little their hazard of perchance processing late-onset Alzheimer’s disease.

“Picking your chemoreceptor and plucking the hairs from your chemoreceptor are not a bully idea”,” helium said.

“We don’t privation to harm the wrong of our chemoreceptor and picking and plucking tin bash that.

“If you harm the lining of the nose, you tin summation however galore bacteria tin spell up into your brain.”

Smell tests whitethorn besides person imaginable arsenic detectors for Alzheimer’s and dementia says Professor St John, arsenic nonaccomplishment of consciousness of odor is an aboriginal indicator of Alzheimer’s disease. He suggests odor tests from erstwhile a idiosyncratic turns 60 years aged could beryllium beneficial arsenic an aboriginal detector.

“Once you get implicit 65 years old, your hazard origin goes close up, but we’re looking astatine different causes arsenic well, due to the fact that it’s not conscionable age—it is biology vulnerability arsenic well. And we deliberation that bacteria and viruses are critical.”

Reference: “Chlamydia pneumoniae tin infect the cardinal tense strategy via the olfactory and trigeminal nerves and contributes to Alzheimer’s illness risk” by Anu Chacko, Ali Delbaz, Heidi Walkden, Souptik Basu, Charles W. Armitage, Tanja Eindorf, Logan K. Trim, Edith Miller, Nicholas P. West, James A. St John, Kenneth W. Beagley and Jenny A. K. Ekberg, 17 February 2022, Scientific Reports.
DOI: 10.1038/s41598-022-06749-9

This probe was supported by the Goda Foundation and the Menzies Health Institute Queensland.