At slightest 5 radical person been killed successful a Russian rocket onslaught connected residential buildings successful the eastbound Ukrainian municipality of Pokrovsk, officials say.
Four civilians and an authoritative were killed, and 31 radical were injured, interior curate Ihor Klymenko said.
President Volodymyr Zelensky said determination were "victims" successful the attack, but did not supply a figure.
Rescue efforts were continuing.
Pokrovsk lies astir 70km (43 miles) north-west of Donetsk city, which is occupied by Russian forces.
Mr Klymenko said the archetypal onslaught killed 4 civilians, and that an authoritative from the exigency services was killed successful the 2nd strike.
The injured included 19 constabulary officers, 5 rescuers and a child, helium said.
Mr Zelensky said the Russian attacks had struck an "ordinary residential building", publishing a video of a five-storey gathering that had its apical level destroyed.
Amid scenes of wide chaos and disorder it showed civilians clearing distant rubble, and rescuers helping radical into ambulances.
Pavlo Krylenko, the caput of the Donetsk region, said the strikes damaged 2 "private assemblage residential buildings, a hotel, catering establishments, shops and administrative buildings".
He warned of the "threat of repeated attacks" and urged residents to instrumentality shelter.
Andriy Yermak, caput of Ukraine's Presidential Office, said astatine slightest 2 civilians were besides killed erstwhile Russian guided bombs deed "private houses" successful Kharkiv Region connected Monday evening.
Five radical were injured successful those attacks, helium said.
The attacks came a time aft a Russian "guided bomb" deed a humor transfusion centre successful north-eastern Ukraine, sidesplitting 2 people, according to Ukrainian officials.